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In the CY 2025 PFS final rule (89 FR 98228 through 98313), to implement sections 11101 and 11102 of the IRA, we codified these requirements and established other policies for the Medicare Part B Drug Inflation Rebate Program and the Medicare Part D Drug Inflation Rebate Program (collectively referred to as the “Medicare Prescription Drug Inflation Rebate Program”) in regulatory text at parts 427 and 428 under title 42, chapter IV of the Code of Federal Regulations for Part B and Part D, respectively

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In patients with T2D, human amylin is known to accumulate in the pancreatic islets of Langerhans, forming oligomer aggregates that contribute to beta-cell damage in T2D