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Functional and Structural Diversity of Insect Glutathione S-transferases in Xenobiotic Adaptation

Indeed, intracellular GSH ( r = 0.78, P = 0.003) and GSH:GSSG ( r = 0.60, P = 0.038) positively correlated with the SLC7A11/15LO1 protein ratio, without relation to intracellular GSSG

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[5] [8] [12] When the need for ribose 5-phosphate is much greater than that for NADPH When significantly more ribose 5-phosphate than NADPH is required, as in rapidly dividing cells with high rates of nucleotide synthesis, precursors of DNA, the oxidative phase of the pentose phosphate pathway is bypassed , and NADPH is not produced