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Neuroprotection in Ischemic Models In models of cerebral ischemia, where neurons are deprived of oxygen and glucose, certain neuropeptides have been associated with: Reduced tissue damage in affected brain regions Preservation of neuronal density in surrounding areas Activation of anti-apoptotic (cell-survival) pathways These effects are thought to involve both neurotrophic signaling and modulation of inflammatory responses, contributing to cellular resilience under stress conditions